166 may refer to:
- 166 (year)
- 166 (number)
- ONE 166, a combat sport event produced by ONE Championship
- EN 166, a European standard concerning eye protection
- UFC 166, a mixed martial arts event held by the Ultimate Fighting Championship
- Ferrari 166, various Ferrari sports cars
- Alfa Romeo 166, an executive sedan
- Radical 166, one of the 20 Kangxi radicals (214 radicals in total) composed of 7 strokes meaning "village" or "li"
- 166 Rhodope, a dark background asteroid from the central region of the asteroid belt
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