| Tournament details | |
|---|---|
| Country | Cuba |
| City | Havana |
| Venue(s) | 1 (in 1 host city) |
| Dates | 20–25 February |
| Teams | 4 |
| Final positions | |
| Champions |  Alacranes del Almendares (1st title) |
| Runner-up |  Cervecería Caracas |
| Tournament statistics | |
| MVP | Agapito Mayor |
The 1949 Caribbean Series was the first edition of the Caribbean Series (Serie del Caribe). It was held from February 20 through February 25 with the champion baseball teams of Cuba, Alacranes del Almendares; Panama, Spur Cola Colonites; Puerto Rico, Indios de Mayagüez and Venezuela, Cervecería Caracas.
The format consisted of 12 games, each team facing the other teams twice, and the games were played at the Estadio del Cerro in Havana, Cuba, which boosted capacity to 35.000 seats. The first pitch was thrown by George Trautman, by then the president of the National Association of Professional Baseball Leagues.