| Tenth edition of the Challenge Desgrange-Colombo | |
| Details | |
|---|---|
| Dates | 19 March – 20 October |
| Location | Europe |
| Races | 11 |
| Champions | |
| Individual champion |  Fred De Bruyne (BEL) (Carpano–Coppi) |
| Nations' champion | Belgium |
The 1957 Challenge Desgrange-Colombo was the tenth edition of the Challenge Desgrange-Colombo. It included eleven races: all the races form the 1956 edition were retained with no additions. Fred De Bruyne won the second of his three individual championships while Belgium retained the nations championship.