| Tournament details | |
|---|---|
| Dates | 18 February – 21 December |
| Teams | 39 (from 39 associations) |
| Final positions | |
| Champions |  Al Ahly (3rd title) |
| Runners-up |  Mamelodi Sundowns |
| Tournament statistics | |
| Matches played | 92 |
| Goals scored | 224 (2.43 per match) |
← 2000 2002 → | |
The 2001 CAF Champions League was the 37th awarding of Africa's premier club football tournament prize organized by the Confederation of African Football (CAF), and the 5th prize under the CAF Champions League format.
In the knockout stage, was added the semifinal rounds so that the runners up as well as the winners from the group stage would progress. In the final, Al Ahly of Egypt defeated Mamelodi Sundowns of South Africa to win their third title.