| Duration | 8 Rounds |
|---|---|
| Highest attendance | 68,250 |
| Broadcast partners | BBC Sport |
| Winners |  St. Helens |
| Runners-up |  Bradford Bulls |
| Biggest home win | 76 – 0 Keighley vs Rochdale Mayfield (Round 3) |
| Biggest away win | 10 – 106 Leeds at Swinton (Round 4) |
| Lance Todd Trophy | Sean Long |
The 2001 Challenge Cup (officially known as the 2001 Silk Cut Challenge Cup for sponsorship reasons) is a rugby league football tournament which began its preliminary stages in December 2000 and ended with the final on 28 April 2001. Bradford Bulls were the reigning champions, following their 24–18 victory over Leeds Rhinos in the 2000 Challenge Cup at Murrayfield Stadium.