| 2010 Mercury Insurance Open | |
|---|---|
| Date | August 2–8 |
| Edition | 30th |
| Category | WTA Premier |
| Draw | 28S /16D |
| Prize money | $700,000 |
| Surface | Hard / outdoor |
| Location | San Diego, California, U.S. |
| Champions | |
| Singles | |
 Svetlana Kuznetsova | |
| Doubles | |
Maria Kirilenko /  Zheng Jie | |
The 2010 Mercury Insurance Open was a women's tennis tournament played on outdoor hard courts. It was the first edition of the Southern California Open since the tournament left the tour in 2007. It was classified as one of the WTA Premier tournaments of the 2010 WTA Tour. It was played in San Diego, California, United States. Unseeded Svetlana Kuznetsova won the singles title.