The 60th Annual Mobil 1 Twelve Hours of Sebring was a 12-hour automobile endurance race for teams of three drivers each fielding sports prototype and grand touring cars held on March 17, 2012, at the Sebring International Raceway in Sebring, Florida before more than 90,000 spectators. It was the 60th 12 Hours of Sebring and the first round of both the 2012 FIA World Endurance Championship (WEC) and the 2012 American Le Mans Series (ALMS). Le Mans Prototype 1 (LMP1), Le Mans Prototype 2 (LMP2), Le Mans Prototype Challenge (LMPC), Le Mans Grand Touring Endurance (LMGTE), and Grand Touring Challenge (GTC) cars competed in the race.
An Audi R18 TDI shared by Marcel Fässler, André Lotterer and Benoît Tréluyer started from pole position after Lotterer set the fastest overall lap time during qualifying. The car lost the race lead on the opening lap to a sister Audi driven by Rinaldo Capello, Tom Kristensen, and Allan McNish. The trio led all but 66 laps and finished first, four laps ahead of their teammates Timo Bernhard, Romain Dumas, and Loïc Duval. It was Kristensen's sixth Sebring victory, Capello's fifth, McNish's fourth and Audi's tenth. Ryan Dalziel, Enzo Potolicchio and Stéphane Sarrazin of Starworks Motorsport's HPD ARX-03b car in third overall won the WEC LMP2 category and the Level 5 Motorsports HPD entry of João Barbosa, Christophe Bouchut and Scott Tucker won the ALMS' P2 class. The Pescarolo Team of Jean-Christophe Boullion, Emmanuel Collard, and Julien Jousse in a Pescarolo 01 car completed the WEC LMP1 class podium. The only classified finisher in the ALMS' P1 category was Chris Dyson, Steven Kane, and Guy Smith in a Lola B12/60 car.
The CORE Autosport Oreca FLM09 vehicle shared by Burt Frisselle, Alex Popow and E. J. Viso won the PC class by one lap over the PR1/Mathiasen Motorsports team of Ken Dobson, Rudy Junco Jr. and Butch Leitzinger. BMW Team RLL's trio of Joey Hand, Dirk Müller and Jonathan Summerton in a BMW M3 GT2 overcame a final lap collision with an AF Corse entered Ferrari 458 Italia GT2 to win the GT class from Corvette Racing's C6.R entry of Antonio García, Jan Magnussen and Jordan Taylor. After losing the opportunity to win outright in GT due to a last lap spin, AF Corse's Olivier Beretta, Andrea Bertolini, and Marco Cioci won the LMGTE Pro category. The LMGTE Am class was led by the No. 50 Larbre Compétition Corvette until driver Pedro Lamy suffered a driveshaft failure in the final hour, handing the victory to Team Felbermayr-Proton's Porsche 997 GT3-RSR of Christian Ried, Gianluca Roda and Paolo Ruberti. Alex Job Racing won their eighth Sebring category with Townsend Bell, Dion von Moltke, and Bill Sweedler's Porsche 997 GT3 Cup leading the GTC category by one lap over teammates Louis-Philippe Dumoulin, Leh Keen, and Cooper MacNeil.