| 2020 Challenger Ciudad de Guayaquil | |
|---|---|
| Date | 16–23 November |
| Edition | 16th |
| Surface | Clay |
| Location | Guayaquil, Ecuador |
| Champions | |
| Singles | |
 Francisco Cerúndolo | |
| Doubles | |
 Luis David Martínez /  Felipe Meligeni Alves | |
The 2020 Challenger Ciudad de Guayaquil is a professional tennis tournament played on clay courts. It is the sixteenth edition of the tournament which is part of the 2020 ATP Challenger Tour. It will take place in Guayaquil, Ecuador between 16 and 23 November 2020.