| 2021 Nur-Sultan Challenger | |
|---|---|
| Date | 22–28 February |
| Edition | 3rd |
| Surface | Hard (Indoor) |
| Location | Nur-Sultan, Kazakhstan |
| Champions | |
| Singles | |
 Mackenzie McDonald | |
| Doubles | |
 Denys Molchanov /  Aleksandr Nedovyesov | |
The 2021 Nur-Sultan Challenger was a professional tennis tournament played on indoor hard courts. It was the third edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Nur-Sultan, Kazakhstan between 22 and 28 February 2021.