The following lists events that happened during 2021 in East Africa. The countries listed are those described in the United Nations geoscheme for East Africa:
Burundi, 
Comoros, 
Djibouti, 
Eritrea, 
Ethiopia, 
Kenya, 
Madagascar, 
Malawi, 
Mauritius, 
Mayotte, 
Mozambique, Réunion, 
Rwanda, 
Seychelles, 
Somalia, 
South Sudan, 
Tanzania,
Uganda, 
Zambia, 
Zimbabwe.