Names | |
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Preferred IUPAC name
(5-Hydroxy-1H-indol-3-yl)acetic acid | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.000.179 |
KEGG | |
MeSH | Hydroxyindoleacetic+Acid |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H9NO3 | |
Molar mass | 191.186 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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5-Hydroxyindoleacetic acid (5-HIAA) is the main metabolite of serotonin. The metabolic intermediate 5-hydroxyindoleacetaldehyde (5-HIAL) is formed from serotonin by monoamine oxidase (MAO) and then 5-HIAA is formed from 5-HIAL via aldehyde dehydrogenase (ALDH). In chemical analysis of urine samples, 5-HIAA is used to determine serotonin levels in the body.