60S ribosomal protein L7

RPL7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5AJ0
Identifiers
Aliases	RPL7, L7, humL7-1, ribosomal protein L7, ribosomal protein uL30
External IDs	OMIM: 604166; MGI: 98073; HomoloGene: 87772; GeneCards: RPL7; OMA:RPL7 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	73,295,789 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	16,174,886 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; Achilles tendon; ; ventricular zone; ; left ovary; ; gastric mucosa; ; right ovary; ; canal of the cervix; ; monocyte; ; smooth muscle tissue; ; body of uterus;
	Top expressed in
	epiblast; ; ventricular zone; ; ganglionic eminence; ; blastocyst; ; uterus; ; zone of skin; ; lens; ; morula; ; esophagus; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein homodimerization activity; DNA binding; mRNA binding; RNA binding; structural constituent of ribosome;
Cellular component	ribosome; nucleolus; cytoplasm; cytosol; nucleus; membrane; focal adhesion; extracellular exosome; polysome; cytosolic large ribosomal subunit; postsynaptic density; ribonucleoprotein complex;
Biological process	SRP-dependent cotranslational protein targeting to membrane; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); viral transcription; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytoplasmic translation; ribosomal large subunit biogenesis; translational initiation; protein biosynthesis; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	6129
	19989
	ENSG00000147604
	ENSMUSG00000043716
	P18124
	P14148
	NM_000971; NM_001363737
	NM_011291
	NP_000962; NP_001350666
	NP_035421
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L7 is a protein that in humans is encoded by the RPL7 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000147604 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043716 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Seshadri T, Uzman JA, Oshima J, Campisi J (September 1993). "Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene". The Journal of Biological Chemistry. 268 (25): 18474–80. doi:10.1016/S0021-9258(17)46650-6. PMID 8360149.
^ Hemmerich P, von Mikecz A, Neumann F, Sözeri O, Wolff-Vorbeck G, Zoebelein R, Krawinkel U (January 1993). "Structural and functional properties of ribosomal protein L7 from humans and rodents". Nucleic Acids Research. 21 (2): 223–31. doi:10.1093/nar/21.2.223. PMC 309096. PMID 8441630.
^ "Entrez Gene: RPL7 ribosomal protein L7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000147604 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043716 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8360149-5] Seshadri T, Uzman JA, Oshima J, Campisi J (September 1993). "Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene". The Journal of Biological Chemistry. 268 (25): 18474–80. doi:10.1016/S0021-9258(17)46650-6. PMID 8360149.

[pmid8441630-6] Hemmerich P, von Mikecz A, Neumann F, Sözeri O, Wolff-Vorbeck G, Zoebelein R, Krawinkel U (January 1993). "Structural and functional properties of ribosomal protein L7 from humans and rodents". Nucleic Acids Research. 21 (2): 223–31. doi:10.1093/nar/21.2.223. PMC 309096. PMID 8441630.

[entrez-7] "Entrez Gene: RPL7 ribosomal protein L7".

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