A1CF

A1CF
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CPD
Identifiers
Aliases	A1CF, ACF, ACF64, ACF65, APOBEC1CF, ASP, APOBEC1 complementation factor
External IDs	OMIM: 618199; MGI: 1917115; HomoloGene: 16363; GeneCards: A1CF; OMA:A1CF - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	50,885,675 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	31,926,395 bp
RNA expression pattern
	Top expressed in
	liver; ; jejunal mucosa; ; mucosa of ileum; ; right lobe of liver; ; buccal mucosa cell; ; duodenum; ; mucosa of colon; ; mucosa of sigmoid colon; ; oocyte; ; pancreatic ductal cell;
	Top expressed in
	right kidney; ; proximal tubule; ; embryo; ; yolk sac; ; liver; ; duodenum; ; left lobe of liver; ; lumbar subsegment of spinal cord; ; jejunum; ; human kidney;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleic acid binding; double-stranded RNA binding; protein binding; single-stranded RNA binding; RNA binding; mRNA binding;
Cellular component	cytoplasm; apolipoprotein B mRNA editing enzyme complex; endoplasmic reticulum; nucleus; nucleoplasm;
Biological process	mRNA processing; protein stabilization; cytidine to uridine editing; mRNA modification; mRNA localization resulting in posttranscriptional regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	29974
	69865
	ENSG00000148584
	ENSMUSG00000052595
	Q9NQ94
	Q5YD48
NM_001198818; NM_001198819; NM_001198820; NM_014576; NM_138932;
	NM_138933; NM_001370130; NM_001370131
	NM_001081074; NM_001365078
NP_001185747; NP_001185748; NP_001185749; NP_055391; NP_620310;
	NP_620311; NP_001357059; NP_001357060
	NP_001074543; NP_001352007
	Wikidata
View/Edit Human	View/Edit Mouse

APOBEC1 complementation factor is a protein that in humans is encoded by the A1CF gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000148584 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052595 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dance GS, Sowden MP, Cartegni L, Cooper E, Krainer AR, Smith HC (April 2002). "Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing". J. Biol. Chem. 277 (15): 12703–9. doi:10.1074/jbc.M111337200. PMID 11815617.
^ Chester A, Scott J, Anant S, Navaratnam N (December 2000). "RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA". Biochim. Biophys. Acta. 1494 (1–2): 1–13. doi:10.1016/S0167-4781(00)00219-0. PMID 11072063.
^ "Entrez Gene: A1CF APOBEC1 complementation factor".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000148584 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000052595 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11815617-5] Dance GS, Sowden MP, Cartegni L, Cooper E, Krainer AR, Smith HC (April 2002). "Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing". J. Biol. Chem. 277 (15): 12703–9. doi:10.1074/jbc.M111337200. PMID 11815617.

[pmid11072063-6] Chester A, Scott J, Anant S, Navaratnam N (December 2000). "RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA". Biochim. Biophys. Acta. 1494 (1–2): 1–13. doi:10.1016/S0167-4781(00)00219-0. PMID 11072063.

[entrez-7] "Entrez Gene: A1CF APOBEC1 complementation factor".

[1]

[2]

[3]

[4]

[5]

[6]

[7]