The A20, or address line 20, is one of the electrical lines that make up the system bus of an x86-based computer system. The A20 line in particular is used to transmit the 21st bit on the address bus.
A microprocessor typically has a number of address lines equal to the base-two logarithm of the number of words in its physical address space. For example, a processor with 4 GB of byte-addressable physical space requires 32 lines (log2(4 GB) = log2(232 B) = 32), which are named A0 through A31. The lines are named after the zero-based number of the bit in the address that they are transmitting. The least significant bit is first and is therefore numbered bit 0 and signaled on line A0. A20 transmits bit 20 (the 21st bit) and becomes active once addresses reach 1 MB, or 220.