AA amyloidosis

AA amyloidosis
AA amyloidosis
Specialty	Rheumatology

AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest during inflammation.^[1]

^ Lachmann HJ, Goodman HJ, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD, et al. (June 2007). "Natural history and outcome in systemic AA amyloidosis" (PDF). The New England Journal of Medicine. 356 (23): 2361–2371. doi:10.1056/NEJMoa070265. PMID 17554117. S2CID 18801734. Archived from the original (PDF) on 2014-01-09.

[pmid17554117-1] Lachmann HJ, Goodman HJ, Gilbertson JA, Gallimore JR, Sabin CA, Gillmore JD, et al. (June 2007). "Natural history and outcome in systemic AA amyloidosis" (PDF). The New England Journal of Medicine. 356 (23): 2361–2371. doi:10.1056/NEJMoa070265. PMID 17554117. S2CID 18801734. Archived from the original (PDF) on 2014-01-09.

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