ABHD2

ABHD2
Identifiers
AliasesABHD2, HS1-2, LABH2, PHPS1-2, abhydrolase domain containing 2
External IDsOMIM: 612196; MGI: 1914344; HomoloGene: 23121; GeneCards: ABHD2; OMA:ABHD2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007011
NM_152924

NM_018811

RefSeq (protein)

NP_008942
NP_690888
NP_008942.3
NP_690888.1

NP_061281

Location (UCSC)Chr 15: 89.09 – 89.2 MbChr 7: 78.92 – 79.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Abhydrolase domain-containing protein 2 is a serine hydrolase enzyme that is strongly expressed in human spermatozoa. It is a key controller of sperm hyperactivation, which is a necessary step in allowing sperm to fertilize an egg.[5] It is encoded by the ABHD2 gene.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140526Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039202Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Preventing sperm's 'power kick' could be key to unisex contraceptive". Berkeley News. 2016-03-17. Retrieved 2017-09-13.
  6. ^ "Entrez Gene: ABHD2 abhydrolase domain containing 2".