ABHD6

ABHD6
Identifiers
Aliases	ABHD6, abhydrolase domain containing 6, abhydrolase domain containing 6, acylglycerol lipase
External IDs	OMIM: 616966; MGI: 1913332; HomoloGene: 23246; GeneCards: ABHD6; OMA:ABHD6 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	58,295,693 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	14,466,871 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; jejunal mucosa; ; lateral nuclear group of thalamus; ; corpus callosum; ; C1 segment; ; endothelial cell; ; cerebellar vermis; ; right lobe of liver; ; duodenum; ; external globus pallidus;
	Top expressed in
	motor neuron; ; adrenal gland; ; facial motor nucleus; ; Rostral migratory stream; ; anterior horn of spinal cord; ; duodenum; ; lateral geniculate nucleus; ; dentate gyrus of hippocampal formation granule cell; ; left lobe of liver; ; pontine nuclei;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; hydrolase activity; acylglycerol lipase activity; phospholipase activity;
Cellular component	integral component of membrane; plasma membrane; AMPA glutamate receptor complex; membrane; mitochondrion; glutamatergic synapse; GABA-ergic synapse; integral component of postsynaptic membrane; lysosomal membrane; late endosome membrane; lysosome; endosome; mitochondrial membranes;
Biological process	acylglycerol catabolic process; negative regulation of cell migration; positive regulation of lipid biosynthetic process; regulation of endocannabinoid signaling pathway; phospholipid catabolic process; long-term depression; negative regulation of cold-induced thermogenesis; monoacylglycerol catabolic process; lysobisphosphatidic acid metabolic process; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	57406
	66082
	ENSG00000163686
	ENSMUSG00000025277
	Q9BV23
	Q8R2Y0
	NM_020676; NM_001320126
	NM_025341; NM_001331064; NM_001331065
	NP_001307055; NP_065727; NP_065727.4; NP_001307055.1
	NP_001317993; NP_001317994; NP_079617
	Wikidata
View/Edit Human	View/Edit Mouse

alpha/beta-Hydrolase domain containing 6 (ABHD6), also known as monoacylglycerol lipase ABHD6 or 2-arachidonoylglycerol hydrolase is an enzyme that in humans is encoded by the ABHD6 gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163686 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025277 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163686 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025277 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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