ACOT13

ACOT13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F0X, 2H4U, 3F5O
Identifiers
Aliases	ACOT13, PNAS-27, THEM2, HT012, acyl-CoA thioesterase 13
External IDs	OMIM: 615652; MGI: 1914084; HomoloGene: 41273; GeneCards: ACOT13; OMA:ACOT13 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	24,705,065 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	25,015,523 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; myocardium of left ventricle; ; apex of heart; ; triceps brachii muscle; ; Achilles tendon; ; right auricle; ; right ventricle; ; muscle of thigh; ; left testis; ; right testis;
	Top expressed in
	interventricular septum; ; myocardium of ventricle; ; right ventricle; ; cardiac muscles; ; right kidney; ; cardiac muscle tissue of left ventricle; ; extraocular muscle; ; digastric muscle; ; masseter muscle; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; acyl-CoA hydrolase activity;
Cellular component	cytosol; spindle; extracellular exosome; cytoskeleton; mitochondrion; nucleus; cytoplasm;
Biological process	protein homotetramerization; acyl-CoA metabolic process; negative regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	55856
	66834
	ENSG00000112304
	ENSMUSG00000006717
	Q9NPJ3
	Q9CQR4
	NM_018473; NM_001160094
	NM_025790
	NP_001153566; NP_060943
	NP_080066
	Wikidata
View/Edit Human	View/Edit Mouse

Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene.^[5] This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112304 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000006717 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Acyl-CoA thioesterase 13".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112304 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000006717 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Acyl-CoA thioesterase 13".

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