ACTR1A

ACTR1A
Identifiers
Aliases	ACTR1A, ARP1, CTRN1, Arp1A, ARP1 actin-related protein 1 homolog A, centractin alpha, ARP1 actin related protein 1 homolog A, actin related protein 1A
External IDs	OMIM: 605143; MGI: 1858964; HomoloGene: 21173; GeneCards: ACTR1A; OMA:ACTR1A - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	102,502,712 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	46,384,187 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; gastrocnemius muscle; ; prefrontal cortex; ; right frontal lobe; ; stromal cell of endometrium; ; muscle layer of sigmoid colon; ; cingulate gyrus; ; anterior cingulate cortex; ; apex of heart; ; C1 segment;
	Top expressed in
	otic vesicle; ; saccule; ; spermatocyte; ; otic placode; ; spermatid; ; facial motor nucleus; ; lip; ; ganglionic eminence; ; external carotid artery; ; internal carotid artery;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	ATP binding; nucleotide binding; protein binding; cytoskeletal protein-membrane anchor activity;
Cellular component	cytosol; microtubule cytoskeleton; microtubule associated complex; cytoplasm; myelin sheath; centrosome; microtubule organizing center; cytoskeleton; extracellular exosome; dynactin complex; manchette; centriole; COPI-coated vesicle; cell cortex region; cell cortex;
Biological process	G2/M transition of mitotic cell cycle; antigen processing and presentation of exogenous peptide antigen via MHC class II; vesicle-mediated transport; spermatogenesis; ciliary basal body-plasma membrane docking; endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of G2/M transition of mitotic cell cycle; establishment of mitotic spindle orientation; nuclear migration along microtubule;
	Sources:Amigo / QuickGO
Orthologs
	10121
	54130
	ENSG00000138107
	ENSMUSG00000025228
	P61163
	P61164
	NM_005736
	NM_016860; NM_001365070
	NP_005727
	NP_058556; NP_001351999
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-centractin (yeast) or ARP1 is a protein that in humans is encoded by the ACTR1A gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138107 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025228 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lees-Miller JP, Helfman DM, Schroer TA (Oct 1992). "A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility". Nature. 359 (6392): 244–6. Bibcode:1992Natur.359..244L. doi:10.1038/359244a0. PMID 1528266. S2CID 4239305.
^ "Entrez Gene: ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000138107 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025228 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1528266-5] Lees-Miller JP, Helfman DM, Schroer TA (Oct 1992). "A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility". Nature. 359 (6392): 244–6. Bibcode:1992Natur.359..244L. doi:10.1038/359244a0. PMID 1528266. S2CID 4239305.

[entrez-6] "Entrez Gene: ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)".

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