ADP/ATP translocase 1

SLC25A4
Identifiers
Aliases	SLC25A4, AAC1, ANT, ANT 1, ANT1, MTDPS12, PEO2, PEO3, T1, PEOA2, solute carrier family 25 member 4, MTDPS12A
External IDs	OMIM: 103220; MGI: 1353495; HomoloGene: 36058; GeneCards: SLC25A4; OMA:SLC25A4 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	185,150,382 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	46,664,321 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; right ventricle; ; apex of heart; ; cardiac muscle tissue of right atrium; ; body of tongue; ; triceps brachii muscle; ; vastus lateralis muscle; ; thoracic diaphragm; ; right auricle; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	atrioventricular valve; ; endocardial cushion; ; atrium; ; myocardium of ventricle; ; cardiac muscles; ; gastrocnemius muscle; ; plantaris muscle; ; extensor digitorum longus muscle; ; interventricular septum; ; right ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transporter activity; protein binding; adenine transmembrane transporter activity; ATP:ADP antiporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; myelin sheath; integral component of plasma membrane; mitochondrion; nucleus; mitochondrial inner membrane; integral component of mitochondrial membrane;
Biological process	mitochondrial genome maintenance; regulation of insulin secretion; negative regulation of necroptotic process; generation of precursor metabolites and energy; apoptotic mitochondrial changes; transmembrane transport; viral process; adenine transport; ATP transport; regulation of mitochondrial membrane permeability; ADP transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	291
	11739
	ENSG00000151729
	ENSMUSG00000031633
	P12235
	P48962
	NM_001151
	NM_007450
	NP_001142
	NP_031476
	Wikidata
View/Edit Human	View/Edit Mouse

ADP/ATP translocase 1, or adenine nucleotide translocator 1 (ANT1), is an enzyme that in humans is encoded by the SLC25A4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000151729 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031633 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fan YS, Yang HM, Lin CC (June 1992). "Assignment of the human muscle adenine nucleotide translocator gene (ANT1) to 4q35 by fluorescence in situ hybridization". Cytogenetics and Cell Genetics. 60 (1): 29–30. doi:10.1159/000133288. PMID 1582253.
^ "Entrez Gene: SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000151729 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031633 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1582253-5] Fan YS, Yang HM, Lin CC (June 1992). "Assignment of the human muscle adenine nucleotide translocator gene (ANT1) to 4q35 by fluorescence in situ hybridization". Cytogenetics and Cell Genetics. 60 (1): 29–30. doi:10.1159/000133288. PMID 1582253.

[entrez-6] "Entrez Gene: SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4".

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