AKT1

AKT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT serine/threonine kinase 1
External IDsOMIM: 164730; MGI: 87986; HomoloGene: 3785; GeneCards: AKT1; OMA:AKT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001165894
NM_009652
NM_001331107

RefSeq (protein)

NP_001159366
NP_001318036
NP_033782

Location (UCSC)Chr 14: 104.77 – 104.8 MbChr 12: 112.62 – 112.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RAC(Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains.[5] It is commonly referred to as PKB, or by both names as "Akt/PKB".

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000142208Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001729Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: AKT1 v-akt murine thymoma viral oncogene homolog 1".