ANP32B

ANP32B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ELL, 2RR6
Identifiers
Aliases	ANP32B, APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B
External IDs	MGI: 1914878; HomoloGene: 21286; GeneCards: ANP32B; OMA:ANP32B - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	98,015,943 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	46,472,657 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; trabecular bone; ; optic nerve; ; thymus; ; internal globus pallidus; ; corpus epididymis; ; cartilage tissue; ; dorsal motor nucleus of vagus nerve; ; parotid gland; ; caput epididymis;
	Top expressed in
	tail of embryo; ; genital tubercle; ; zygote; ; primary oocyte; ; secondary oocyte; ; bone marrow; ; epiblast; ; yolk sac; ; ventricular zone; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	histone binding; protein binding; RNA polymerase binding;
Cellular component	cytoplasm; extracellular exosome; nucleolus; nucleus;
Biological process	positive regulation of protein export from nucleus; negative regulation of cell differentiation; inner ear development; nucleosome assembly; roof of mouth development; vasculature development; activation of cysteine-type endopeptidase activity involved in apoptotic process; ventricular system development; histone exchange;
	Sources:Amigo / QuickGO
Orthologs
	10541
	67628
	ENSG00000136938
	ENSMUSG00000028333
	Q92688
	Q9EST5
	NM_006401
	NM_130889
	NP_006392
	NP_570959
	Wikidata
View/Edit Human	View/Edit Mouse

Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) also known as "acidic protein rich in leucines" (APRIL) is a protein that in humans is encoded by the ANP32B gene.^[5]^[6]^[7]

APRIL is also the acronym used for an entirely different protein, TNFSF13, a member of the tumor necrosis factor superfamily whose alternative name, A PRoliferation Inducing Ligand, shares the same acronym as that for ANP32B

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136938 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028333 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhu L, Perlaky L, Henning D, Valdez BC (Jan 1998). "Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family". Biochem Mol Biol Int. 42 (5): 927–35. doi:10.1080/15216549700203371. PMID 9285060. S2CID 19749385.
^ Mencinger M, Panagopoulos I, Contreras JA, Mitelman F, Aman P (Mar 1998). "Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines". Biochim Biophys Acta. 1395 (2): 176–80. doi:10.1016/S0167-4781(97)00165-6. PMID 9473664.
^ "Entrez Gene: ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136938 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028333 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9285060-5] Zhu L, Perlaky L, Henning D, Valdez BC (Jan 1998). "Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family". Biochem Mol Biol Int. 42 (5): 927–35. doi:10.1080/15216549700203371. PMID 9285060. S2CID 19749385.

[pmid9473664-6] Mencinger M, Panagopoulos I, Contreras JA, Mitelman F, Aman P (Mar 1998). "Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines". Biochim Biophys Acta. 1395 (2): 176–80. doi:10.1016/S0167-4781(97)00165-6. PMID 9473664.

[entrez-7] "Entrez Gene: ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B".

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