ASCC3

ASCC3
Identifiers
Aliases	ASCC3, ASC1p200, HELIC1, RNAH, activating signal cointegrator 1 complex subunit 3
External IDs	OMIM: 614217; MGI: 1925237; HomoloGene: 4973; GeneCards: ASCC3; OMA:ASCC3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	100,881,372 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	50,727,581 bp
RNA expression pattern
	Top expressed in
	decidua; ; secondary oocyte; ; Achilles tendon; ; gonad; ; stromal cell of endometrium; ; ventricular zone; ; testicle; ; islet of Langerhans; ; bone marrow cells; ; right coronary artery;
	Top expressed in
	spermatid; ; tail of embryo; ; gastrula; ; spermatocyte; ; genital tubercle; ; epithelium of small intestine; ; supraoptic nucleus; ; hand; ; ascending aorta; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; 3'-5' DNA helicase activity; protein binding; hydrolase activity; ATP binding; helicase activity; nucleic acid binding; RNA binding;
Cellular component	intracellular anatomical structure; membrane; nucleoplasm; nucleus; cytosol; activating signal cointegrator 1 complex; nuclear speck; cytoplasm; Golgi apparatus;
Biological process	DNA dealkylation involved in DNA repair; DNA duplex unwinding; cell population proliferation; regulation of transcription, DNA-templated; transcription, DNA-templated; cellular response to DNA damage stimulus; DNA repair;
	Sources:Amigo / QuickGO
Orthologs
	10973
	77987
	ENSG00000112249
	ENSMUSG00000038774
	Q8N3C0
	E9PZJ8
	NM_001284271; NM_006828; NM_022091
	NM_198007
	NP_001271200; NP_006819; NP_071374
	NP_932124
	Wikidata
View/Edit Human	View/Edit Mouse

Activating signal cointegrator 1 complex subunit 3 is a protein that in humans is encoded by the ASCC3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112249 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038774 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Coulie PG, Ikeda H, Baurain JF, Chiari R (Jun 1999). "Antitumor immunity at work in a melanoma patient". Advances in Cancer Research. 76: 213–42. doi:10.1016/S0065-230X(08)60778-2. ISBN 978-0-12-006676-6. PMID 10218103.
^ "Entrez Gene: ASCC3 activating signal cointegrator 1 complex subunit 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112249 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038774 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10218103-5] Coulie PG, Ikeda H, Baurain JF, Chiari R (Jun 1999). "Antitumor immunity at work in a melanoma patient". Advances in Cancer Research. 76: 213–42. doi:10.1016/S0065-230X(08)60778-2. ISBN 978-0-12-006676-6. PMID 10218103.

[entrez-6] "Entrez Gene: ASCC3 activating signal cointegrator 1 complex subunit 3".

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