ASCL1

ASCL1
Identifiers
AliasesASCL1, ASH1, HASH1, MASH1, bHLHa46, achaete-scute family bHLH transcription factor 1
External IDsOMIM: 100790; MGI: 96919; HomoloGene: 31234; GeneCards: ASCL1; OMA:ASCL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004316

NM_008553

RefSeq (protein)

NP_004307

NP_032579

Location (UCSC)Chr 12: 102.96 – 102.96 MbChr 10: 87.33 – 87.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Achaete-scute homolog 1 is a protein that in humans is encoded by the ASCL1 gene.[5][6] Because it was discovered subsequent to studies on its homolog in Drosophila, the Achaete-scute complex, it was originally named MASH-1 for mammalian achaete scute homolog-1.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000139352Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020052Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ball DW, Azzoli CG, Baylin SB, Chi D, Dou S, Donis-Keller H, et al. (June 1993). "Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors". Proceedings of the National Academy of Sciences of the United States of America. 90 (12): 5648–52. Bibcode:1993PNAS...90.5648B. doi:10.1073/pnas.90.12.5648. PMC 46778. PMID 8390674.
  6. ^ "Entrez Gene: ASCL1 achaete-scute complex homolog 1 (Drosophila)".
  7. ^ Sanes DH (2011). The development of the nervous system. Elsevier. ISBN 978-0-12-374539-2.