ATP5B

ATP5F1B
Identifiers
Aliases	ATP5F1B, ATPMB, ATPSB, HEL-S-271, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, ATP synthase F1 subunit beta, ATP5B
External IDs	OMIM: 102910; MGI: 107801; HomoloGene: 1273; GeneCards: ATP5F1B; OMA:ATP5F1B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,645,984 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	127,926,260 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; right auricle; ; right ventricle; ; myocardium of left ventricle; ; mucosa of transverse colon; ; cerebellar cortex; ; right hemisphere of cerebellum; ; muscle of thigh; ; gastrocnemius muscle;
	Top expressed in
	right kidney; ; dentate gyrus of hippocampal formation granule cell; ; myocardium of ventricle; ; right ventricle; ; atrium; ; central gray substance of midbrain; ; mandibular prominence; ; cardiac muscles; ; human kidney; ; maxillary prominence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; transmembrane transporter activity; transporter activity; proton-transporting ATPase activity, rotational mechanism; ATPase activity; protein binding; MHC class I protein binding; hydrolase activity; ATP binding; angiostatin binding; proton-transporting ATP synthase activity, rotational mechanism;
Cellular component	mitochondrial proton-transporting ATP synthase complex; membrane; mitochondrial membranes; myelin sheath; plasma membrane; cell surface; mitochondrial matrix; mitochondrial proton-transporting ATP synthase, catalytic core; mitochondrion; mitochondrial inner membrane; proton-transporting ATP synthase complex, catalytic core F(1); mitochondrial nucleoid; extracellular exosome; nucleus; extracellular matrix; proton-transporting ATP synthase complex; proton-transporting two-sector ATPase complex, catalytic domain;
Biological process	lipid metabolism; mitochondrial ATP synthesis coupled proton transport; mitochondrion organization; regulation of intracellular pH; ion transport; generation of precursor metabolites and energy; negative regulation of cell adhesion involved in substrate-bound cell migration; ATP metabolic process; angiogenesis; osteoblast differentiation; ATP synthesis coupled proton transport; ATP biosynthetic process; cristae formation; positive regulation of blood vessel endothelial cell migration; transport; cellular response to interleukin-7; proton transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	506
	11947
	ENSG00000110955
	ENSMUSG00000025393
	P06576
	P56480
	NM_001686
	NM_016774
	NP_001677
	NP_058054
	Wikidata
View/Edit Human	View/Edit Mouse

ATP synthase F1 subunit beta, mitochondrial is an enzyme that in humans is encoded by the ATP5F1B gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110955 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025393 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Neckelmann N, Warner CK, Chung A, Kudoh J, Minoshima S, Fukuyama R, Maekawa M, Shimizu Y, Shimizu N, Liu JD (Jan 1990). "The human ATP synthase beta subunit gene: sequence analysis, chromosome assignment, and differential expression". Genomics. 5 (4): 829–43. doi:10.1016/0888-7543(89)90125-0. PMID 2687158.
^ "Entrez Gene: ATP5F1B ATP synthase F1 subunit beta".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000110955 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025393 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2687158-5] Neckelmann N, Warner CK, Chung A, Kudoh J, Minoshima S, Fukuyama R, Maekawa M, Shimizu Y, Shimizu N, Liu JD (Jan 1990). "The human ATP synthase beta subunit gene: sequence analysis, chromosome assignment, and differential expression". Genomics. 5 (4): 829–43. doi:10.1016/0888-7543(89)90125-0. PMID 2687158.

[entrez-6] "Entrez Gene: ATP5F1B ATP synthase F1 subunit beta".

[1]

[2]

[3]

[4]

[5]

[6]