ATP6V1E2

ATP6V1E2
Identifiers
Aliases	ATP6V1E2, ATP6E1, ATP6EL2, ATP6V1EL2, VMA4, ATPase H+ transporting V1 subunit E2
External IDs	OMIM: 617385; MGI: 1922165; HomoloGene: 41770; GeneCards: ATP6V1E2; OMA:ATP6V1E2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	46,542,577 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	87,255,325 bp
RNA expression pattern
	Top expressed in
	sperm; ; right testis; ; left testis; ; gonad; ; islet of Langerhans; ; white blood cell; ; monocyte; ; testicle; ; C1 segment; ; muscle of thigh;
	Top expressed in
	seminiferous tubule; ; spermatid; ; submandibular gland; ; spermatocyte; ; gastrula; ; mucosa of small intestine; ; lumbar spinal ganglion; ; medial ganglionic eminence; ; right ventricle; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	P-type proton-exporting transporter activity; protein binding; proton-transporting ATPase activity, rotational mechanism;
Cellular component	cytosol; acrosomal vesicle; proton-transporting two-sector ATPase complex, catalytic domain;
Biological process	insulin receptor signaling pathway; ion transmembrane transport; ion transport; transferrin transport; regulation of macroautophagy; phagosome acidification;
	Sources:Amigo / QuickGO
Orthologs
	90423
	74915
	ENSG00000250565
	ENSMUSG00000053375
	Q96A05
	Q9D593
	NM_080653; NM_001318063; NM_001371281; NM_001371282; NM_001371283
	NM_029121
	NP_001304992; NP_001358210; NP_001358211; NP_001358212
	NP_083397
	Wikidata
View/Edit Human	View/Edit Mouse

V-type proton ATPase subunit E 2 is an enzyme that in humans is encoded by the ATP6V1E2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000250565 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053375 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Imai-Senga Y, Sun-Wada GH, Wada Y, Futai M (May 2002). "A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E". Gene. 289 (1–2): 7–12. doi:10.1016/S0378-1119(02)00542-5. PMID 12036578.
^ "Entrez Gene: ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2".