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Abu al-Fatḥ Manuchihr Khan (died 1636), was a Safavid official and gholam of Armenian origin. Like his father Qarachaqay Khan, Manuchihr was established at Mashhad as the general and governor of Khorasan under the shahs (kings) Abbas I (r. 1588–1629) and Ṣāfi (r. 1629–1642). His brother Ali Quli Khan became prefect of Qom and head of the library of Abbas I. Manuchihr Khan's son, Qarachaqay Khan II (d. 1668), became also a governor of Mashhad. All of them were among the Safavid cultural and intellectual elite, known as “men of knowledge and integrity’ (ahl-i fazl u kamāl) and “of illustrious acts and deeds” (ṣāhib-i mu'āṣir u asrār).
