Acipimox

Acipimox
Skeletal formula
Ball-and-stick model
Clinical data
Trade namesOlbetam
AHFS/Drugs.comUK Drug Information
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability100%
Protein bindingNone
MetabolismNone
Elimination half-lifePhase 1: 2 hrs
Phase 2: 12–14 hrs
ExcretionRenal
Identifiers
  • 5-Carboxy-2-methyl-1-oxidopyrazin-1-ium
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.051.736 Edit this at Wikidata
Chemical and physical data
FormulaC6H6N2O3
Molar mass154.125 g·mol−1
3D model (JSmol)
  • [O-][n+]1c(cnc(C(=O)O)c1)C
  • InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10) checkY
  • Key:DJQOOSBJCLSSEY-UHFFFAOYSA-N checkY
  (verify)

Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent. It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.