Acrosin

Acrosin
Identifiers
EC no.3.4.21.10
CAS no.9068-57-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Acrosin is a digestive enzyme that acts as a protease. In humans, acrosin is encoded by the ACR gene.[1][2] Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida.

  1. ^ Adham IM, Klemm U, Maier WM, Engel W (Jan 1990). "Molecular cloning of human preproacrosin cDNA". Human Genetics. 84 (2): 125–8. doi:10.1007/bf00208925. PMID 2298447. S2CID 39848902.
  2. ^ Honda A, Siruntawineti J, Baba T (2002). "Role of acrosomal matrix proteases in sperm-zona pellucida interactions". Human Reproduction Update. 8 (5): 405–12. doi:10.1093/humupd/8.5.405. PMID 12398221.