Acute proliferative glomerulonephritis | |
---|---|
Micrograph of a post-infectious glomerulonephritis. Kidney biopsy. PAS stain. | |
Specialty | Nephrology |
Symptoms | Hypertension[1] |
Causes | Caused by Streptococcus bacteria [2] |
Diagnostic method | Kidney biopsy, Complement profile[2] |
Treatment | Low-sodium diet, Blood pressure management[2] |
Frequency | 1.5 million (2015)[3] |
Acute proliferative glomerulonephritis is a disorder of the small blood vessels of the kidney. It is a common complication of bacterial infections, typically skin infection by Streptococcus bacteria types 12, 4 and 1 (impetigo) but also after streptococcal pharyngitis, for which it is also known as postinfectious glomerulonephritis (PIGN) or poststreptococcal glomerulonephritis (PSGN).[4] It can be a risk factor for future albuminuria.[5] In adults, the signs and symptoms of infection may still be present at the time when the kidney problems develop, and the terms infection-related glomerulonephritis or bacterial infection-related glomerulonephritis are also used.[6] Acute glomerulonephritis resulted in 19,000 deaths in 2013, down from 24,000 deaths in 1990 worldwide.[7]
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