The term Adhesome was first used by Richard Hynes to describe the complement of cell-cell and cell-matrix adhesion receptors in an organism [ 1] and later expanded by Benny Geiger and co-workers to include the entire network of structural and signaling proteins involved in regulating cell-matrix adhesion.[ 2] [ 3] [ 4]
^ Whittaker, Charles A.; Bergeron, Karl-Frederik; Whittle, James; Brandhorst, Bruce P.; Burke, Robert D.; Hynes, Richard O. (December 2006). "The echinoderm adhesome" . Developmental Biology . 300 (1): 252–266. doi :10.1016/j.ydbio.2006.07.044 . PMC 3565218 . PMID 16950242 .
^ Zaidel-Bar, Ronen; Itzkovitz, Shalev; Ma'ayan, Avi; Iyengar, Ravi; Geiger, Benjamin (2007). "Functional atlas of the integrin adhesome" . Nature Cell Biology . 9 (8): 858–867. doi :10.1038/ncb0807-858 . PMC 2735470 . PMID 17671451 .
^ Zaidel-Bar, Ronen; Geiger, Benjamin (2010-05-01). "The switchable integrin adhesome" . J Cell Sci . 123 (9): 1385–1388. doi :10.1242/jcs.066183 . ISSN 0021-9533 . PMC 2858016 . PMID 20410370 .
^ Winograd-Katz, Sabina E.; Fässler, Reinhard; Geiger, Benjamin; Legate, Kyle R. (2014). "The integrin adhesome: from genes and proteins to human disease". Nature Reviews Molecular Cell Biology . 15 (4): 273–288. doi :10.1038/nrm3769 . PMID 24651544 . S2CID 5528372 .