 | This article possibly contains original research. (March 2020) |
Adipose tissue is an endocrine organ that secretes numerous protein hormones, including leptin, adiponectin, and resistin.[1] These hormones generally influence energy metabolism, which is of great interest to the understanding and treatment of type 2 diabetes and obesity.[2]
Their relative roles in modifying appetite, insulin resistance and atherosclerosis are the subjects of intense research, as they may be modifiable causes of morbidity in people with obesity.[3][4]
- ^ Coelho, Marisa; Oliveira, Teresa; Fernandes, Ruben (2013-04-20). "Biochemistry of adipose tissue: an endocrine organ". Archives of Medical Science. 9 (2): 191–200. doi:10.5114/aoms.2013.33181. ISSN 1734-1922. PMC 3648822. PMID 23671428.
- ^ Scheja, Ludger; Heeren, Joerg (September 2019). "The endocrine function of adipose tissues in health and cardiometabolic disease". Nature Reviews Endocrinology. 15 (9): 507–524. doi:10.1038/s41574-019-0230-6. ISSN 1759-5037. PMID 31296970. S2CID 195892443.
- ^ Matsuzawa Y, Funahashi T, Nakamura T (November 1999). "Molecular mechanism of metabolic syndrome X: contribution of adipocytokines adipocyte-derived bioactive substances". Ann. N. Y. Acad. Sci. 892 (1): 146–54. Bibcode:1999NYASA.892..146M. doi:10.1111/j.1749-6632.1999.tb07793.x. PMID 10842660. S2CID 22802586.
- ^ Funahashi T, Nakamura T, Shimomura I, et al. (February 1999). "Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity". Intern. Med. 38 (2): 202–6. doi:10.2169/internalmedicine.38.202. PMID 10225688.