Alpha-2-HS-glycoprotein

AHSG
Identifiers
Aliases	AHSG, A2HS, AHS, FETUA, HSGA, alpha-2-HS-glycoprotein, alpha 2-HS glycoprotein
External IDs	OMIM: 138680; MGI: 107189; HomoloGene: 1225; GeneCards: AHSG; OMA:AHSG - orthologs
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	22,718,199 bp
RNA expression pattern
	n/a
	Top expressed in
	left lobe of liver; ; gallbladder; ; fetal liver hematopoietic progenitor cell; ; human fetus; ; right atrium; ; left atrium; ; sexually immature organism; ; atrioventricular valve; ; tongue muscle; ; morula;
	; ;
	More reference expression data
Gene ontology
Molecular function	endopeptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity; kinase inhibitor activity;
Cellular component	blood microparticle; extracellular exosome; platelet alpha granule lumen; extracellular space; Golgi apparatus; secretory granule lumen; endoplasmic reticulum lumen; extracellular matrix; extracellular region; collagen-containing extracellular matrix;
Biological process	regulation of bone mineralization; negative regulation of biomineral tissue development; skeletal system development; negative regulation of insulin receptor signaling pathway; positive regulation of phagocytosis; pinocytosis; negative regulation of bone mineralization; acute-phase response; ossification; regulation of inflammatory response; negative regulation of phosphorylation; platelet degranulation; negative regulation of endopeptidase activity; neutrophil degranulation; post-translational protein modification; negative regulation of kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	197
	11625
	ENSG00000145192
	ENSMUSG00000022868
	P02765
	P29699
	NM_001622
	NM_001276449; NM_001276450; NM_013465
	NP_001613; NP_001341500; NP_001341501; NP_001341502
	NP_001263378; NP_001263379; NP_038493
	Wikidata
View/Edit Human	View/Edit Mouse

alpha-2-HS-glycoprotein (AHSG, Alpha-2-Heremans-Schmid Glycoprotein) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene.^[4]^[5]^[6] Fetuin-A belongs to the fetuin class of plasma binding proteins and is more abundant in fetal than adult blood.

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022868 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rizzu P, Baldini A (1995). "Three members of the human cystatin gene superfamily, AHSG, HRG, and KNG, map within one megabase of genomic DNA at 3q27". Cytogenet. Cell Genet. 70 (1–2): 26–8. doi:10.1159/000133984. PMID 7736783.
^ Osawa M, Umetsu K, Sato M, Ohki T, Yukawa N, Suzuki T, Takeichi S (September 1997). "Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG)". Gene. 196 (1–2): 121–5. doi:10.1016/S0378-1119(97)00216-3. PMID 9322749.
^ "Entrez Gene: AHSG alpha-2-HS-glycoprotein".

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000022868 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7736783-4] Rizzu P, Baldini A (1995). "Three members of the human cystatin gene superfamily, AHSG, HRG, and KNG, map within one megabase of genomic DNA at 3q27". Cytogenet. Cell Genet. 70 (1–2): 26–8. doi:10.1159/000133984. PMID 7736783.

[pmid9322749-5] Osawa M, Umetsu K, Sato M, Ohki T, Yukawa N, Suzuki T, Takeichi S (September 1997). "Structure of the gene encoding human alpha 2-HS glycoprotein (AHSG)". Gene. 196 (1–2): 121–5. doi:10.1016/S0378-1119(97)00216-3. PMID 9322749.

[entrez-6] "Entrez Gene: AHSG alpha-2-HS-glycoprotein".

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