Ambroxol

Ambroxol
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	oral, inhaled, intramuscular, intravenous
ATC code	R05CB06 (WHO) R02AD05 (WHO);
Legal status
Legal status	In general: Over-the-counter (OTC);
Identifiers
	IUPAC name trans-4-(2-Amino-3,5-dibromobenzylamino)-cyclohexanol;
CAS Number	18683-91-5 ;
PubChem CID	2132;
ChemSpider	10276826 ;
UNII	200168S0CL;
KEGG	D07442 ;
ChEMBL	ChEMBL153479 ;
CompTox Dashboard (EPA)	DTXSID8022583 ;
ECHA InfoCard	100.038.621
Chemical and physical data
Formula	C13H18Br2N2O
Molar mass	378.108 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O;
	InChI InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2/t10-,11- ; Key:JBDGDEWWOUBZPM-XYPYZODXSA-N ;
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Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup.

It was patented in 1966 and came into medical use in 1979.^[1]

^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 544. ISBN 9783527607495.

[Fis2006-1] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 544. ISBN 9783527607495.

[1]

Clinical data


AHFS/Drugs.com	International Drug Names
Routes of administration	oral, inhaled, intramuscular, intravenous
ATC code	R05CB06 (WHO) R02AD05 (WHO)
Legal status
Legal status	In general: Over-the-counter (OTC)
Identifiers
IUPAC name trans-4-(2-Amino-3,5-dibromobenzylamino)-cyclohexanol
CAS Number	18683-91-5^N
PubChem CID	2132
ChemSpider	10276826^Y
UNII	200168S0CL
KEGG	D07442^Y
ChEMBL	ChEMBL153479^Y
CompTox Dashboard (EPA)	DTXSID8022583
ECHA InfoCard	100.038.621
Chemical and physical data
Formula	C₁₃H₁₈Br₂N₂O
Molar mass	378.108 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O
InChI InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2/t10-,11-^Y Key:JBDGDEWWOUBZPM-XYPYZODXSA-N^Y
^NY (what is this?) (verify)