| Anaplasma phagocytophilum | |
|---|---|
| |
| Human HL60 cells containing Anaplasma phagocytophilum (indicated by arrows) which are basophilic intracytoplasmic inclusions when stained with Wright-Giemsa stain | |
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Alphaproteobacteria |
| Order: | Rickettsiales |
| Family: | Ehrlichiaceae |
| Genus: | Anaplasma |
| Species: | A. phagocytophilum
|
| Binomial name | |
| Anaplasma phagocytophilum (Foggie 1949) Dumler et al. 2001[1]
| |
| Synonyms | |
|
Rickettsia phagocytophila ovis | |
Anaplasma phagocytophilum (formerly Ehrlichia phagocytophilum)[2] is a Gram-negative bacterium that is unusual in its tropism to neutrophils. It causes anaplasmosis in sheep and cattle, also known as tick-borne fever and pasture fever, and also causes the zoonotic disease human granulocytic anaplasmosis.[3]
A. phagocytophilum is a Gram-negative, obligate bacterium of neutrophils. It causes human granulocytic anaplasmosis, which is a tick-borne rickettsial disease. Because this bacterium invades neutrophils, it has a unique adaptation and pathogenetic mechanism.[4]
- ^ Page Anaplasma on lpsn.dsmz.de
- ^ Dumler JS, Barbet AF, Bekker CP, et al. (2001). "Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila". Int. J. Syst. Evol. Microbiol. 51 (Pt 6): 2145–65. doi:10.1099/00207713-51-6-2145. PMID 11760958.
- ^ Tick-Borne Fever reviewed and published by WikiVet, accessed 12 October 2011.
- ^ Dumler JS, Choi KS, Garcia-Garcia JC, et al. (December 2005). "Human granulocytic anaplasmosis and Anaplasma phagocytophilum". Emerging Infect. Dis. 11 (12): 1828–34. doi:10.3201/eid1112.050898. PMC 3367650. PMID 16485466.