Angiotensin II receptor

angiotensin II receptor, type 1
Identifiers
SymbolAGTR1
Alt. symbolsAGTR1B
IUPHAR34
NCBI gene185
HGNC336
OMIM106165
RefSeqNM_000685
UniProtP30556
Other data
LocusChr. 3 q21-q25
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StructuresSwiss-model
DomainsInterPro
angiotensin II receptor, type 2
Identifiers
SymbolAGTR2
IUPHAR35
NCBI gene186
HGNC338
OMIM300034
RefSeqNM_000686
UniProtP50052
Other data
LocusChr. X q22-q23
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StructuresSwiss-model
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The angiotensin II receptors, (ATR1) and (ATR2), are a class of G protein-coupled receptors with angiotensin II as their ligands.[1] They are important in the renin–angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II.[2]

  1. ^ de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T (September 2000). "International union of pharmacology. XXIII. The angiotensin II receptors". Pharmacological Reviews. 52 (3): 415–72. PMID 10977869.
  2. ^ Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S (April 2007). "Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology". Clinical Science. 112 (8): 417–28. doi:10.1042/CS20060342. PMID 17346243. S2CID 27624282.