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| Anna of Hohenstaufen | |
|---|---|
 Sepulchre of Constance in the Church San Juan del Hospital (Valencia). The inscription translates as Here lies Lady Constance Augusta, Empress of Greece | |
| Empress consort of Nicaea | |
| Tenure | 1244–1254 |
| Born | 1230 |
| Died | April 1307 (age 76–77) |
| Spouse | John III Doukas Vatatzes |
| Father | Frederick II, Holy Roman Emperor |
| Mother | Bianca Lancia |
Anna of Hohenstaufen (1230 – April 1307), born Constance, was an Empress of Nicaea. She was a daughter of Frederick II, Holy Roman Emperor and Bianca Lancia.