Anti-Jo1

Anti-Jo1 is an anti-nuclear antibody.[1][2]

Anti-Jo1 has been associated with inflammatory myopathies such as polymyositis, dermatomyositis and antisynthetase syndrome.[3][4]

It has histidine-tRNA ligase as a target.

  1. ^ Gutiérrez-Ramos R; Gonzalez-Díaz V; Pacheco-Tovar MG; López-Luna A; Avalos-Díaz E; Herrera-Esparza R (2008). "A dermatomyositis and scleroderma overlap syndrome with a remarkable high titer of anti-exosome antibodies" (PDF). Reumatismo. 60 (4): 296–300. doi:10.4081/reumatismo.2008.296. PMID 19132155.
  2. ^ Zold E; Szodoray P; Gaal J; et al. (2008). "Vitamin D deficiency in undifferentiated connective tissue disease". Arthritis Res. Ther. 10 (5): R123. doi:10.1186/ar2533. PMC 2592813. PMID 18928561.
  3. ^ Kalenian M; Zweiman B (March 1997). "Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association". Clinical and Diagnostic Laboratory Immunology. 4 (2): 236–40. doi:10.1128/CDLI.4.2.236-240.1997. PMC 170510. PMID 9067664.
  4. ^ "Antisynthetase syndrome". Orphanet. Retrieved 20 March 2019.