| Apostolic Nunciature to the Czech Republic | |
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| Location | Prague, Czech Republic. |
| Address | Voršilská 140, 110 00 Nové Město, Prague, Czech Republic. |
| Coordinates | 50°04′52.0″N 14°25′00.0″E / 50.081111°N 14.416667°E |
| Apostolic Nuncio | Archbishop Jude Thaddeus Okolo |
The Apostolic Nunciature to the Czech Republic (Czech: Apoštolská nunciatura v České republice) the diplomatic mission of the Holy See to the Czech Republic. It is located in Prague. The current Apostolic Nuncio is Archbishop Jude Thaddeus Okolo, who was named to the position by Pope Francis on 1 May 2022.
The nunciature is an ecclesiastical office of the Catholic Church in the Czech Republic, with the rank of an embassy. The nuncio serves both as the ambassador of the Holy See to the President of the Czech Republic, and as delegate and point-of-contact between the Catholic hierarchy in the Czech Republic and the pope.