Aristaless related homeobox

ARX
Identifiers
Aliases	ARX, CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS, aristaless related homeobox
External IDs	OMIM: 300382; MGI: 1097716; HomoloGene: 68998; GeneCards: ARX; OMA:ARX - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	25,016,420 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	92,341,963 bp
RNA expression pattern
	Top expressed in
	left ovary; ; right ovary; ; ventricular zone; ; vastus lateralis muscle; ; germinal epithelium; ; endothelial cell; ; bronchial epithelial cell; ; Brodmann area 23; ; biceps brachii; ; cingulate gyrus;
	Top expressed in
	Rostral migratory stream; ; medial ganglionic eminence; ; Gonadal ridge; ; ventricular zone; ; olfactory bulb; ; uterine tube; ; temporal muscle; ; nucleus accumbens; ; efferent ductule; ; ovary;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; chromatin binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; cerebral cortex tangential migration; lipid digestion; positive regulation of organ growth; neuron migration; negative regulation of transcription by RNA polymerase II; globus pallidus development; transcription, DNA-templated; nervous system development; axon guidance; multicellular organism development; positive regulation of gene expression; regulation of cell population proliferation; epithelial cell fate commitment; embryonic olfactory bulb interneuron precursor migration; cerebral cortex GABAergic interneuron migration; forebrain development; olfactory bulb development; cell proliferation in forebrain; neuron development;
	Sources:Amigo / QuickGO
Orthologs
	170302
	11878
	ENSG00000004848
	ENSMUSG00000035277
	Q96QS3
	O35085
	NM_139058
	NM_007492; NM_001305940
	NP_620689
	NP_001292869; NP_031518
	Wikidata
View/Edit Human	View/Edit Mouse

Aristaless related homeobox is a protein that in humans is encoded by the ARX gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000004848 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035277 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: ARX aristaless related homeobox".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000004848 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035277 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ARX aristaless related homeobox".

[1]

[2]

[3]

[4]

[5]