Artemin

ARTN
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ASK, 2GH0, 2GYR, 2GYZ
Identifiers
Aliases	ARTN, ENOVIN, EVN, NBN, artemin, ART
External IDs	OMIM: 603886; MGI: 1333791; HomoloGene: 7631; GeneCards: ARTN; OMA:ARTN - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	43,937,240 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	117,786,960 bp
RNA expression pattern
	Top expressed in
	testicle; ; triceps brachii muscle; ; mucosa of transverse colon; ; trachea; ; gastric mucosa; ; pituitary gland; ; pericardium; ; prostate; ; anterior pituitary; ; pons;
	Top expressed in
	embryo; ; seminiferous tubule; ; spermatid; ; vas deferens; ; embryo; ; zygote; ; transitional epithelium of urinary bladder; ; morula; ; right kidney; ; cornea;
	More reference expression data
	n/a
Gene ontology
Molecular function	growth factor activity; signaling receptor binding; protein binding;
Cellular component	extracellular region; intracellular anatomical structure; extracellular space;
Biological process	induction of positive chemotaxis; neuroblast proliferation; lymphocyte migration into lymphoid organs; peripheral nervous system development; signal transduction; Peyer's patch morphogenesis; MAPK cascade; axon guidance; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	9048
	11876
	ENSG00000117407
	ENSMUSG00000028539
	Q5T4W7
	Q9Z0L2
	NM_001136215; NM_003976; NM_057090; NM_057091; NM_057160
	NM_009711; NM_001284191; NM_001284192; NM_001284193
	NP_001129687; NP_476431; NP_476432
	NP_001271120; NP_001271121; NP_001271122; NP_033841
	Wikidata
View/Edit Human	View/Edit Mouse

Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117407 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028539 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: artemin".
^ Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, et al. (December 1998). "Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex". Neuron. 21 (6): 1291–302. doi:10.1016/S0896-6273(00)80649-2. PMID 9883723. S2CID 18633359.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117407 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028539 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: artemin".

[pmid9883723-6] Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, et al. (December 1998). "Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex". Neuron. 21 (6): 1291–302. doi:10.1016/S0896-6273(00)80649-2. PMID 9883723. S2CID 18633359.

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