At risk mental state

At risk mental state is the clinical presentation of those considered at risk of developing psychosis or schizophrenia.[1] Such states were formerly considered treated as prodromes, emerging symptoms of psychosis, but this view is no longer prevalent as a prodromal period can not be confirmed unless the emergence of the condition has occurred.[citation needed]

The original specialist service for those with subclinical symptoms of psychosis was The Pace Clinic[2] in Melbourne, Australia.[3] Other clinics have since developed around the world.[4][5][6][7]

There has been some considerable development of how the concept can be applied clinically.[8][9][10][11]

Assessed during the structured interview developed by PACE[clarification needed].[12]

  1. ^ Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakkar A (1996). "Monitoring and care of young people at incipient risk of psychosis". Schizophr Bull. 22 (2): 283–303. doi:10.1093/schbul/22.2.283. PMID 8782287.
  2. ^ "ORYGEN Youth Health". Archived from the original on 2009-10-24. Retrieved 2011-08-04.
  3. ^ Yung AR, McGorry PD, McFarlane CA, Jackson HJ, Patton GC, Rakkar A (1996). "Monitoring and care of young people at incipient risk of psychosis". Schizophr Bull. 22 (2): 283–303. doi:10.1093/schbul/22.2.283. PMID 8782287.
  4. ^ Broome MR, Woolley JB, Johns LC, et al. (August 2005). "Outreach and support in south London (OASIS): implementation of a clinical service for prodromal psychosis and the at risk mental state". Eur. Psychiatry. 20 (5–6): 372–8. doi:10.1016/j.eurpsy.2005.03.001. PMID 16171652. S2CID 27207646.
  5. ^ PRIME
  6. ^ (COPE)
  7. ^ "Emory University". Archived from the original on 2011-07-22. Retrieved 2011-08-04.
  8. ^ Yung AR, Phillips LJ, Yuen HP, et al. (March 2003). "Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group". Schizophr. Res. 60 (1): 21–32. doi:10.1016/S0920-9964(02)00167-6. PMID 12505135. S2CID 31342026.
  9. ^ McGorry PD, Yung AR, Phillips LJ, et al. (October 2002). "Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms". Arch. Gen. Psychiatry. 59 (10): 921–8. doi:10.1001/archpsyc.59.10.921. hdl:10536/DRO/DU:30151296. PMID 12365879.
  10. ^ Morrison AP, French P, Parker S, et al. (May 2007). "Three-year follow-up of a randomized controlled trial of cognitive therapy for the prevention of psychosis in people at ultrahigh risk". Schizophr Bull. 33 (3): 682–7. doi:10.1093/schbul/sbl042. PMC 2526150. PMID 16973786.
  11. ^ Schäfer Amminger; Papageorgiou Harrigan; Cotton McGorry, Berger (2008). "Indicated Prevention of Psychotic Disorders with Long-Chainomega-3 Fatty Acids: A Randomized, Placebo-Controlled Trial". Schizophrenia Research. 102 (1–3): 252. doi:10.1016/s0920-9964(08)70758-8. S2CID 53301111.
  12. ^ Yung AR, Yuen HP, McGorry PD, et al. (2005). "Mapping the onset of psychosis: the Comprehensive Assessment of At-Risk Mental States". Aust N Z J Psychiatry. 39 (11–12): 964–71. doi:10.1080/j.1440-1614.2005.01714.x. PMID 16343296. S2CID 145477493.