Look up BESM in Wiktionary, the free dictionary.
BESM is a line of Soviet-made mainframe computers.
BESM may also refer to:
- BESm (N1, N12-bis(ethyl)spermine), a derivative of spermine
- Best estimate stress model, a method for estimating rock stress in rock mechanics
- Big Eyes, Small Mouth, a role-playing game
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