BOC (gene)

BOC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3N1G, 3N1M, 3N1P
Identifiers
Aliases	BOC, CDON2, BOC cell adhesion associated, oncogene regulated, Boi
External IDs	OMIM: 608708; MGI: 2151153; HomoloGene: 32819; GeneCards: BOC; OMA:BOC - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	113,287,459 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	44,379,260 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; ventricular zone; ; left uterine tube; ; skin of arm; ; gastric mucosa; ; parotid gland; ; skin of thigh; ; right uterine tube; ; body of uterus; ; tibia;
	Top expressed in
	ventricular zone; ; skin of external ear; ; efferent ductule; ; internal carotid artery; ; vas deferens; ; lip; ; trachea; ; ascending aorta; ; conjunctival fornix; ; aortic valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; axonal growth cone; integral component of plasma membrane; membrane; nucleoplasm;
Biological process	smoothened signaling pathway; cell adhesion; positive regulation of myoblast differentiation; positive regulation of muscle cell differentiation; axon guidance;
	Sources:Amigo / QuickGO
Orthologs
	91653
	117606
	ENSG00000144857
	ENSMUSG00000022687
	Q9BWV1
	Q6AZB0
NM_001301861; NM_001301867; NM_033254; NM_001378073; NM_001378074;
	NM_001378075; NM_001387919; NM_001387920; NM_001387921; NM_001387922; NM_001387923; NM_001387924; NM_001387925; NM_001387926; NM_001387927; NM_001387928; NM_001387929; NM_001387930; NM_001387932
	NM_172506
NP_001288790; NP_001288796; NP_150279; NP_001365002; NP_001365003;
	NP_001365004
	NP_766094
	Wikidata
View/Edit Human	View/Edit Mouse

Brother of CDO is a protein that in humans is encoded by the BOC gene.^[5]^[6]

CDON (MIM 608707) and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144857 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022687 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kang JS, Mulieri PJ, Hu Y, Taliana L, Krauss RS (Jan 2002). "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation". EMBO J. 21 (1–2): 114–24. doi:10.1093/emboj/21.1.114. PMC 125805. PMID 11782431.
^ ^a ^b "Entrez Gene: BOC Boc homolog (mouse)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000144857 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022687 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11782431-5] Kang JS, Mulieri PJ, Hu Y, Taliana L, Krauss RS (Jan 2002). "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation". EMBO J. 21 (1–2): 114–24. doi:10.1093/emboj/21.1.114. PMC 125805. PMID 11782431.

[entrez-6] "Entrez Gene: BOC Boc homolog (mouse)".

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