Barbital

Barbital
Clinical data
Trade names	Veronal, Medinal
AHFS/Drugs.com	International Drug Names
MedlinePlus	a682221
Routes of; administration	Oral
ATC code	N05CA04 (WHO) ;
Legal status
Legal status	BR: Class B1 (Psychoactive drugs); CA: Schedule IV; DE: Anlage III (Special prescription form required); US: Schedule IV;
Pharmacokinetic data
Elimination half-life	30.3 (± 3.2) hours
Identifiers
	IUPAC name 5,5-diethylpyrimidine-2,4,6(1H,3H,5H)-trione;
CAS Number	57-44-3 ;
PubChem CID	2294;
DrugBank	DB01483 ;
ChemSpider	2206 ;
UNII	5WZ53ENE2P;
KEGG	D01740 ;
ChEBI	CHEBI:31252 ;
ChEMBL	ChEMBL444 ;
CompTox Dashboard (EPA)	DTXSID5022643 ;
ECHA InfoCard	100.000.301
Chemical and physical data
Formula	C8H12N2O3
Molar mass	184.195 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=O)NC(=O)C1(CC)CC;
	InChI InChI=1S/C8H12N2O3/c1-3-8(4-2)5(11)9-7(13)10-6(8)12/h3-4H2,1-2H3,(H2,9,10,11,12,13) ; Key:FTOAOBMCPZCFFF-UHFFFAOYSA-N ;
	(verify)

Barbital (or barbitone), marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate. It was used as a sleeping aid (hypnotic) from 1903 until the mid-1950s. The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt (known as medinal, a genericised trademark in the United Kingdom) is known also as sodium diethylbarbiturate.

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

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