Basophilia

Basophilia
Basophilic Granulocyte surrounded by Erythrocytes and a Thrombocyte.
Pronunciation
  • bā-sə-ˈfi-lē-ə
SpecialtyHematology Edit this on Wikidata
CausesChronic myeloid leukemia, polycythemia vera, primary myelofibrosis, essential thrombocythemia, acute myeloid leukemia, allergic reactions or chronic inflammation related to infections, inflammatory bowel disease, and autoimmune disease.
Diagnostic methodComplete blood count and blood smear.

Basophilia is the condition of having greater than 200 basophils/μL in the venous blood.[1] Basophils are the least numerous of the myelogenous cells, and it is rare for their numbers to be abnormally high without changes to other blood components. Rather, basophilia is most often coupled with other white blood cell conditions such as eosinophilia, high levels of eosinophils in the blood.[1] Basophils are easily identifiable by a blue coloration of the granules within each cell, marking them as granulocytes, in addition to segmented nuclei.[2]

  1. ^ a b Sticco, Kristin; Lynch, David (2019-11-07). "Basophilia". National Center for Biotechnology Information, U.S. National Library of Medicine. StatPearls Publishing. PMID 30570986. Retrieved 2020-01-17.
  2. ^ Boiten HJ, de Jongh E (August 2018). "Atypical basophilia". Blood. 132 (5): 551. doi:10.1182/blood-2018-05-849901. PMID 30072416.