| Beta cell | |
|---|---|
| Details | |
| Location | Pancreatic islet |
| Function | Insulin secretion |
| Identifiers | |
| Latin | endocrinocytus B; insulinocytus |
| TH | H3.04.02.0.00026 |
| FMA | 85704 |
| Anatomical terms of microanatomy | |
Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin.[1] Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels.[2] Problems with beta cells can lead to disorders such as diabetes.[3]
- ^ Dolenšek J, Rupnik MS, Stožer A (2015-01-02). "Structural similarities and differences between the human and the mouse pancreas". Islets. 7 (1): e1024405. doi:10.1080/19382014.2015.1024405. PMC 4589993. PMID 26030186. S2CID 17908732.
- ^ Chen C, Cohrs CM, Stertmann J, Bozsak R, Speier S (September 2017). "Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis". Molecular Metabolism. 6 (9): 943–957. doi:10.1016/j.molmet.2017.06.019. PMC 5605733. PMID 28951820.
- ^ Ashcroft FM, Rorsman P (March 2012). "Diabetes mellitus and the β cell: the last ten years". Cell. 148 (6): 1160–1171. doi:10.1016/j.cell.2012.02.010. PMC 5890906. PMID 22424227.