Bicine

Bicine
Names
	IUPAC name N,N-Bis(2-hydroxyethyl)glycine
	Systematic IUPAC name [Bis(2-hydroxyethyl)amino]acetic acid
	Other names Diethylolglycine; Diethanol glycine; Dihydroxyethylglycine; BHG
Identifiers
CAS Number	150-25-4 ;
3D model (JSmol)	Interactive image;
Abbreviations	DHEG
ChEBI	CHEBI:39066 ;
ChEMBL	ChEMBL1231251 ;
ChemSpider	8431 ;
DrugBank	DB03709 ;
ECHA InfoCard	100.005.233
PubChem CID	8761;
UNII	1J484QFI1O ;
CompTox Dashboard (EPA)	DTXSID3041669 ;
	InChI InChI=1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Key: FSVCELGFZIQNCK-UHFFFAOYSA-N ; InChI=1/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11) Key: FSVCELGFZIQNCK-UHFFFAOYAV;
	SMILES O=C(O)CN(CCO)CCO;
Properties
Chemical formula	C6H13NO4
Molar mass	163.17 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C.^[1] It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.^[2]

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O₂, SO₂, H₂S or Thiosulfate.^[3]

^ N,N-Bis(2-hydroxyethyl)glycine at ChEBI
^ The Merck Index (10th ed.). Rahway, NJ: Merck & Co. 1983. p. 453. ISBN 0-911910-27-1.
^ Lawson, Gary (2003). "Amine Plant Corrosion Reduced by Removal of Bicine" (PDF). Gas Processors Association Annual Convention. Archived from the original (PDF) on 2015-06-16. Retrieved 18 March 2016.

[1] N,N-Bis(2-hydroxyethyl)glycine at ChEBI

[Merck-2] The Merck Index (10th ed.). Rahway, NJ: Merck & Co. 1983. p. 453. ISBN 0-911910-27-1.

[3] Lawson, Gary (2003). "Amine Plant Corrosion Reduced by Removal of Bicine" (PDF). Gas Processors Association Annual Convention. Archived from the original (PDF) on 2015-06-16. Retrieved 18 March 2016.

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