Bifidobacterium longum

Bifidobacterium longum
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species:
B. longum
Binomial name
Bifidobacterium longum
Reuter 1963 (Approved Lists 1980)[1]
Representative morphologic characteristics of B. longum subsp. longum strains

Bifidobacterium longum is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the 32 species that belong to the genus Bifidobacterium.[2][3] It is a microaerotolerant anaerobe and considered to be one of the earliest colonizers of the gastrointestinal tract of infants.[2] When grown on general anaerobic medium, B. longum forms white, glossy colonies with a convex shape.[4] B. longum is one of the most common bifidobacteria present in the gastrointestinal tracts of both children and adults.[5] B. longum is non-pathogenic, is often added to food products,[2][6] and its production of lactic acid is believed to prevent growth of pathogenic organisms.[7]

  1. ^ Parte, A.C. "Bifidobacterium". LPSN.
  2. ^ a b c Schell, M. A.; Karmirantzou, M.; Snel, B.; Vilanova, D.; Berger, B.; Pessi, G.; Zwahlen, M. -C.; Desiere, F.; Bork, P.; Delley, M.; Pridmore, R. D.; Arigoni, F. (2002). "The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract". Proceedings of the National Academy of Sciences. 99 (22): 14422–14427. Bibcode:2002PNAS...9914422S. doi:10.1073/pnas.212527599. PMC 137899. PMID 12381787.
  3. ^ Garrido, D.; Ruiz-Moyano, S.; Jimenez-Espinoza, R.; Eom, H. J.; Block, D. E.; Mills, D. A. (2013). "Utilization of galactooligosaccharides by Bifidobacterium longum subsp. Infantis isolates". Food Microbiology. 33 (2): 262–270. doi:10.1016/j.fm.2012.10.003. PMC 3593662. PMID 23200660.
  4. ^ Young Park, Shin; Lee, Do Kyung; Mi An, Hyang; Gyeong Cha, Min; Baek, Eun Hae; Rae Kim, Jung; Lee, Si Won; Kim, Mi Jin; Lee, Kang Oh; Joo Ha, Nam (1 July 2011). "Phenotypic and genotypic characterization of Bifidobacterium isolates from healthy adult Koreans". Iranian Journal of Biotechnology. 9 (3): 173–180. CiteSeerX 10.1.1.833.1384.
  5. ^ Pasolli, Edoardo; Schiffer, Lucas; Manghi, Paolo; Renson, Audrey; Obenchain, Valerie; Truong, Duy Tin; Beghini, Francesco; Malik, Faizan; Ramos, Marcel; Dowd, Jennifer B; Huttenhower, Curtis; Morgan, Martin; Segata, Nicola; Waldron, Levi (November 2017). "Accessible, curated metagenomic data through ExperimentHub". Nature Methods. 14 (11): 1023–1024. doi:10.1038/nmeth.4468. PMC 5862039. PMID 29088129.
  6. ^ Yazawa, Kazuyuki; Fujimori, Minoru; Amano, Jun; Kano, Yasunobu; Taniguchi, Shun'ichiro (February 2000). "Bifidobacterium longum as a delivery system for cancer gene therapy: Selective localization and growth in hypoxic tumors". Cancer Gene Therapy. 7 (2): 269–274. doi:10.1038/sj.cgt.7700122. PMID 10770636. S2CID 7375660.
  7. ^ Yuan, Jing; Zhu, Li; Liu, Xiankai; Li, Ting; Zhang, Ying; Ying, Tianyi; Wang, Bin; Wang, Junjun; Dong, Hua; Feng, Erling; Li, Qiang; Wang, Jie; Wang, Hongxia; Wei, Kaihua; Zhang, Xuemin; Huang, Cuifeng; Huang, Peitang; Huang, Liuyu; Zeng, Ming; Wang, Hengliang (June 2006). "A Proteome Reference Map and Proteomic Analysis of Bifidobacterium longum NCC2705". Molecular & Cellular Proteomics. 5 (6): 1105–1118. doi:10.1074/mcp.M500410-MCP200. PMID 16549425.