Bile salt sulfotransferase

SULT2A1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1EFH, 1J99, 1OV4, 2QP3, 2QP4, 3F3Y, 4IFB
Identifiers
Aliases	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa, sulfotransferase family 2A member 1, DHEA-ST8, SULT2A3
External IDs	OMIM: 125263; MGI: 3645854; HomoloGene: 37741; GeneCards: SULT2A1; OMA:SULT2A1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	47,886,315 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	13,723,532 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; jejunal mucosa; ; right lobe of liver; ; left adrenal cortex; ; duodenum; ; gonad; ; buccal mucosa cell; ; seminal vesicula; ; cardia; ; mucosa of ileum;
	Top expressed in
	primary oocyte; ; zygote; ; secondary oocyte; ; spermatocyte; ; spermatid; ; gonad; ; testicle; ; liver;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; protein binding; estrone sulfotransferase activity; aryl sulfotransferase activity; steroid sulfotransferase activity; bile-salt sulfotransferase activity;
Cellular component	cytoplasm; cytosol;
Biological process	lipid catabolic process; bile acid catabolic process; sulfation; lipid metabolism; ethanol catabolic process; regulation of lipid metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; steroid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	6822
	434121
	ENSG00000105398
	ENSMUSG00000074377
	Q06520
	n/a
	NM_003167
	NM_001101534
	NP_003158
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Bile salt sulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by the SULT2A1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105398 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074377 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1".
^ Otterness DM, Wieben ED, Wood TC, Watson WG, Madden BJ, McCormick DJ, Weinshilboum RM (May 1992). "Human liver dehydroepiandrosterone sulfotransferase: molecular cloning and expression of cDNA". Mol. Pharmacol. 41 (5): 865–72. PMID 1588921.
^ Otterness DM, Mohrenweiser HW, Brandriff BF, Weinshilboum RM (1995). "Dehydroepiandrosterone sulfotransferase gene (STD): localization to human chromosome band 19q13.3". Cytogenet. Cell Genet. 70 (1–2): 45–7. doi:10.1159/000133988. PMID 7736787.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105398 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000074377 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1".

[pmid1588921-6] Otterness DM, Wieben ED, Wood TC, Watson WG, Madden BJ, McCormick DJ, Weinshilboum RM (May 1992). "Human liver dehydroepiandrosterone sulfotransferase: molecular cloning and expression of cDNA". Mol. Pharmacol. 41 (5): 865–72. PMID 1588921.

[pmid7736787-7] Otterness DM, Mohrenweiser HW, Brandriff BF, Weinshilboum RM (1995). "Dehydroepiandrosterone sulfotransferase gene (STD): localization to human chromosome band 19q13.3". Cytogenet. Cell Genet. 70 (1–2): 45–7. doi:10.1159/000133988. PMID 7736787.

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